IL27 Antibody - C-terminal region (ARP60748_P050)

Data Sheet
 
Product Number ARP60748_P050
Product Page www.avivasysbio.com/il27-antibody-c-terminal-region-arp60748-p050.html
Name IL27 Antibody - C-terminal region (ARP60748_P050)
Protein Size (# AA) 243 amino acids
Molecular Weight 27kDa
Subunit alpha
NCBI Gene Id 246778
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Interleukin 27
Alias Symbols p28, IL30, IL-27, IL27A, IL-27A, IL27p28
Peptide Sequence Synthetic peptide located within the following region: AQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLSPQ
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Protein Interactions IL27RA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-IL27 (ARP60748_P050) antibody
Blocking Peptide For anti-IL27 (ARP60748_P050) antibody is Catalog # AAP60748 (Previous Catalog # AAPP46941)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human IL27
Uniprot ID Q8NEV9
Protein Name Interleukin-27 subunit alpha
Protein Accession # NP_663634
Purification Affinity Purified
Nucleotide Accession # NM_145659
Tested Species Reactivity Human
Gene Symbol IL27
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human Fetal Lung
WB Suggested Anti-IL27 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Lung
 

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