DAXX Antibody - N-terminal region : FITC (ARP60159_P050-FITC)

Data Sheet
 
Product Number ARP60159_P050-FITC
Product Page www.avivasysbio.com/daxx-antibody-n-terminal-region-fitc-arp60159-p050-fitc.html
Name DAXX Antibody - N-terminal region : FITC (ARP60159_P050-FITC)
Protein Size (# AA) 740 amino acids
Molecular Weight 81kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 1616
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols DAP6, EAP1, BING2, SMIM40
Peptide Sequence Synthetic peptide located within the following region: KLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Protein Interactions FAM9B; SSX2IP; SUMO1; UBE2I; UBC; GOLGA2; CARD9; PBXIP1; CDCA7L; NECAB2; RASSF1; PML; MDM2; H3F3A; DNMT1; TP53; ATRX; CARM1; PRMT1; WHSC1L1; CUL3; SPOP; HIPK2; PDCD4; DNMT3A; USP7; UBB; RELB; DAXX; CREB1; CBS; ATM; HIST1H4F; HIST1H3C; TRAF3; HIST4H4; BTBD
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-DAXX (ARP60159_P050-FITC) antibody
Blocking Peptide For anti-DAXX (ARP60159_P050-FITC) antibody is Catalog # AAP60159
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAXX
Uniprot ID Q9UER7
Protein Accession # NP_001341
Purification Affinity Purified
Gene Symbol DAXX
Predicted Species Reactivity Human
Application WB
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