ADORA3 Antibody - C-terminal region (ARP59956_P050)

• Product Number: ARP59956_P050
• Name: ADORA3 Antibody - C-terminal region (ARP59956_P050)
• Protein Size (# AA): 266 amino acids
• Molecular Weight: 30kDa
• NCBI Gene Id: 140
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Adenosine A3 receptor
• Alias Symbols: A3AR
• Peptide Sequence: Synthetic peptide located within the following region: RSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRV
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
• Protein Interactions: YWHAQ; YWHAZ;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-ADORA3 (ARP59956_P050) antibody is Catalog # AAP59956 (Previous Catalog # AAPP46118)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3
• Uniprot ID: Q5QNY7
• Protein Name: Protein ADORA3, isoform 3
• Publications:

  Merighi, S. et al. Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol. Pharmacol. 72, 162-72 (2007). 17400763

• Protein Accession #: NP_001075445
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001081976
• Tested Species Reactivity: Human
• Gene Symbol: ADORA3
• Predicted Species Reactivity: Human, Cow, Horse, Pig, Rabbit
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 75%; Horse: 93%; Human: 100%; Pig: 85%; Rabbit: 77%
• Image 1: Human Oral Carcinoma
  
  Sample type -- Oral Cell Carcinoma Dilution -- 5ug/mL
• Image 2: Human Lung
  
  WB Suggested Anti-ADORA3 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: Human Lung