Product Number |
ARP59946_P050 |
Product Page |
www.avivasysbio.com/add3-antibody-c-terminal-region-arp59946-p050.html |
Name |
ADD3 Antibody - C-terminal region (ARP59946_P050) |
Protein Size (# AA) |
706 amino acids |
Molecular Weight |
78kDa |
NCBI Gene Id |
120 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Adducin 3 (gamma) |
Alias Symbols |
ADDL, CPSQ3 |
Peptide Sequence |
Synthetic peptide located within the following region: DELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. |
Protein Interactions |
UBC; RNF2; HDAC8; ATXN1; SUMO1; PRKCA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ADD3 (ARP59946_P050) antibody |
Blocking Peptide |
For anti-ADD3 (ARP59946_P050) antibody is Catalog # AAP59946 (Previous Catalog # AAPP46109) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ADD3 |
Uniprot ID |
Q9UEY8 |
Protein Name |
Gamma-adducin |
Protein Accession # |
NP_001112 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001121 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
ADD3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IF, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human THP1
| WB Suggested Anti-ADD3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: THP-1 cell lysate |
| Image 2 | mouse HEI-OCI auditory
| mouse HEI-OCI auditory |
|
|