| Product Number |
ARP59265_P050 |
| Product Page |
www.avivasysbio.com/cdh1-antibody-middle-region-arp59265-p050.html |
| Name |
CDH1 Antibody - middle region (ARP59265_P050) |
| Protein Size (# AA) |
882 amino acids |
| Molecular Weight |
80kDa |
| NCBI Gene Id |
999 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cadherin 1, type 1, E-cadherin (epithelial) |
| Alias Symbols |
UVO, CDHE, ECAD, LCAM, Arc-1, BCDS1, CD324 |
| Peptide Sequence |
Synthetic peptide located within the following region: FSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. |
| Protein Interactions |
UBC; MDM2; UCHL3; CDC27; PTEN; CTNNB1; PIP5K1C; CTNND1; CBLL1; RNF2; GMNN; LMNA; KRT18; KRT9; KRT8; KRT1; IGHA1; HSPD1; HSP90AA1; HSPA9; HSPA8; HSPA5; GBAS; CTNNA1; CRYAB; CFTR; C1QBP; ACTN4; ACADVL; ANP32B; NIPSNAP1; XRCC5; TGM2; SKP2; SET; RAD17; POLR2E |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for ARP59265_P050 |
| Blocking Peptide |
Catalog # AAP59265 (Previous Catalog # AAPP45252) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human CDH1 |
| Uniprot ID |
P12830 |
| Protein Name |
Cadherin-1 |
| Protein Accession # |
NP_004351 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004360 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDH1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 92%; Zebrafish: 93% |
| Image 1 | Human HeLa
 | Sample Type: HeLa whole cell lysatePrimary Dilution: 1:200 |
|
| Image 2 | Human Lung
 | WB Suggested Anti-CDH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Lung |
|
