| Product Number |
ARP59145_P050 |
| Product Page |
www.avivasysbio.com/nfatc1-antibody-n-terminal-region-arp59145-p050.html |
| Name |
NFATC1 Antibody - N-terminal region (ARP59145_P050) |
| Protein Size (# AA) |
353 amino acids |
| Molecular Weight |
38kDa |
| NCBI Gene Id |
4772 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| Alias Symbols |
NFAT2, NFATc, NF-ATC, NF-ATc1.2 |
| Peptide Sequence |
Synthetic peptide located within the following region: HVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. |
| Protein Interactions |
YWHAQ; OGT; PML; GZF1; FOXP3; HDAC4; PIAS1; SUMO1; UBE2I; RPS6KB1; RPS6KA3; HDAC2; HDAC1; HNRNPA1; TUBA1A; KPNB1; HDAC5; KAT2B; EP300; PARP1; HDAC3; PPP3R1; MAPK14; GNB2L1; PRKCA; SPI1; PIM1; EGR2; EGR1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NFATC1 (ARP59145_P050) antibody |
| Blocking Peptide |
For anti-NFATC1 (ARP59145_P050) antibody is Catalog # AAP59145 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1 |
| Uniprot ID |
O95644 |
| Protein Name |
Nuclear factor of activated T-cells, cytoplasmic 1 |
| Protein Accession # |
NP_765976 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_172388 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NFATC1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Brain
 | WB Suggested Anti-NFATC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human brain |
|
