| Product Number |
ARP58874_P050 |
| Product Page |
www.avivasysbio.com/becn1-antibody-middle-region-arp58874-p050.html |
| Name |
BECN1 Antibody - middle region (ARP58874_P050) |
| Protein Size (# AA) |
450 amino acids |
| Molecular Weight |
50kDa |
| NCBI Gene Id |
8678 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Beclin 1, autophagy related |
| Alias Symbols |
ATG6, VPS30, beclin1 |
| Peptide Sequence |
Synthetic peptide located within the following region: ENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
BECN1 plays a central role in autophagy. BECN1 may play a role in antiviral host defense. BECN1 protects against infection by a neurovirulent strain of Sindbis virus. |
| Protein Interactions |
AMBRA1; PIK3R4; ATG14; CHAF1A; DYNLL1; UVRAG; PIK3CG; PIK3C3; PARK2; DYNC1I1; DAPK1; CDKN2A; BCL2L1; BCL2; BECN1; DACT1; KIAA0226; UBC; RNF2; BRCA1; WASH1; EXOC8; EXOC4; EXOC2; ULK1; ATG3; USP33; S100A8; MCL1; HSPA1A; Vmp1; PYCARD; TAB2; TAB3; GFI1B; ITCH |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BECN1 (ARP58874_P050) antibody |
| Blocking Peptide |
For anti-BECN1 (ARP58874_P050) antibody is Catalog # AAP58874 (Previous Catalog # AAPP44821) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human BECN1 |
| Uniprot ID |
Q14457 |
| Protein Name |
Beclin-1 |
| Publications |
Alteration of Phospholipids during the Mitophagic Process in Lung Cancer Cells. J. Microbiol. Biotechnol. 26, 1790-1799 (2016). 27363475 |
| Sample Type Confirmation |
BECN1 is strongly supported by BioGPS gene expression data to be expressed in 721_B BECN1 is supported by BioGPS gene expression data to be expressed in HEK293 |
| Protein Accession # |
NP_003757 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003766 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BECN1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HEK-293
 | Lanes:
1: 50ug HEK lysate
Primary Antibody Dilution:
1:100
Secondary Antibody:
Anti-rabbit-RPF
Secondary Antibody Dilution:
1:10,000
Gene Name:
BECN1
Submitted by:
Agathe Korniat INSERM/UPMC UMRS_956
BECN1 is supported by BioGPS gene expression data to be expressed in HEK293 |
|
| Image 2 | Human 721_B
 | WB Suggested Anti-BECN1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysateBECN1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
|
| Image 3 | Human Fetal Heart
 | Host: Rabbit
Target Name: BECN1
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml |
|
| Image 4 | Human Fetal Lung
 | Host: Rabbit
Target Name: BECN1
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
