NRDC Antibody - middle region (ARP58755_P050)

Data Sheet
 
Product Number ARP58755_P050
Product Page www.avivasysbio.com/nrdc-antibody-middle-region-arp58755-p050.html
Name NRDC Antibody - middle region (ARP58755_P050)
Protein Size (# AA) 1151 amino acids
Molecular Weight 132kDa
NCBI Gene Id 4898
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name nardilysin convertase
Alias Symbols NRD1, hNRD1, hNRD2
Peptide Sequence Synthetic peptide located within the following region: GSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Hiraoka,Y., (2008) Biochem. Biophys. Res. Commun. 370 (1), 154-158
Description of Target This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interactions FBXW11; UBC; rev; SETSIP; PUS1; P3H1; ELAC2; XPO5; NSUN2; PDIA6; YARS; DNAJC7; TSN; PPP3CA; PPP2R2A; PPP2CA; PFDN5; PFDN1; PPP1R12A; MSH2; PNKP; HSPB1; MOB2; MOB1A; STK3; NRD1; HIST2H3C; UACA; COBLL1; NCOR2; NCOR1; HDAC3; IQGAP1; MAD1L1; TBL1X; UIMC1; BTR
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NRDC (ARP58755_P050) antibody
Blocking Peptide For anti-NRDC (ARP58755_P050) antibody is Catalog # AAP58755 (Previous Catalog # AAPP38522)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human NRD1
Uniprot ID O43847
Protein Name nardilysin
Protein Accession # NP_001095132
Purification Affinity Purified
Nucleotide Accession # NM_001101662
Tested Species Reactivity Human
Gene Symbol NRDC
Predicted Species Reactivity Human, Cow, Horse, Pig
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Horse: 86%; Human: 100%; Pig: 93%
Image 1
Human HepG2
WB Suggested Anti-NRD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
 

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