| Product Number |
ARP58734_P050 |
| Product Page |
www.avivasysbio.com/thpo-antibody-middle-region-arp58734-p050.html |
| Name |
THPO Antibody - middle region (ARP58734_P050) |
| Protein Size (# AA) |
353 amino acids |
| Molecular Weight |
35kDa |
| NCBI Gene Id |
7066 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Thrombopoietin |
| Alias Symbols |
ML, TPO, MGDF, MKCSF, MPLLG, THCYT1 |
| Peptide Sequence |
Synthetic peptide located within the following region: HELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Baker,J.E., (2008) Cardiovasc. Res. 77 (1), 44-53 |
| Description of Target |
Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. THPO is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
APH1A; NUMBL; EP300; MPL; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-THPO (ARP58734_P050) antibody |
| Blocking Peptide |
For anti-THPO (ARP58734_P050) antibody is Catalog # AAP58734 (Previous Catalog # AAPP38502) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human THPO |
| Uniprot ID |
P40225 |
| Protein Name |
Thrombopoietin |
| Protein Accession # |
NP_000451 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000460 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
THPO |
| Predicted Species Reactivity |
Human, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Horse: 79%; Human: 100% |
| Image 1 | Human MCF-7
 | WB Suggested Anti-THPO Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate |
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