| Product Number |
ARP58728_P050 |
| Product Page |
www.avivasysbio.com/tmed10-antibody-middle-region-arp58728-p050.html |
| Name |
TMED10 Antibody - middle region (ARP58728_P050) |
| Protein Size (# AA) |
219 amino acids |
| Molecular Weight |
24kDa |
| NCBI Gene Id |
10972 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Transmembrane emp24-like trafficking protein 10 (yeast) |
| Alias Symbols |
p23, TMP21, p24d1, S31I125, Tmp-21-I, S31III125, P24(DELTA) |
| Peptide Sequence |
Synthetic peptide located within the following region: KLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Dolcini,V., (2008) Biochem. Biophys. Res. Commun. 371 (1), 69-74 |
| Description of Target |
TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
| Protein Interactions |
UBC; SUMO1; NEDD8; ASB8; RNF2; FBXO6; rev; TMED9; COPZ1; SEC23B; UBL4A; DHODH; ATF2; VCP; PTRF; S100A16; NIT2; PRDX6; SEC22B; EIF3C; VAMP2; COPG1; COPE; COPB2; COPB1; COPA; ARCN1; CDK2; EBNA-LP; RYK; TMED2; PSENEN; APH1A; NCSTN; ARF1; GORASP2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TMED10 (ARP58728_P050) antibody |
| Blocking Peptide |
For anti-TMED10 (ARP58728_P050) antibody is Catalog # AAP58728 (Previous Catalog # AAPP36424) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TMED10 |
| Uniprot ID |
P49755 |
| Protein Name |
Transmembrane emp24 domain-containing protein 10 |
| Protein Accession # |
NP_006818 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006827 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TMED10 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 100% |
| Image 1 | Human Small Intestine
 | WB Suggested Anti-TMED10 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Small Intestine |
|
