| Product Number |
ARP58715_P050 |
| Product Page |
www.avivasysbio.com/trpc3-antibody-n-terminal-region-arp58715-p050.html |
| Name |
TRPC3 Antibody - N-terminal region (ARP58715_P050) |
| Protein Size (# AA) |
848 amino acids |
| Molecular Weight |
97kDa |
| NCBI Gene Id |
7222 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Transient receptor potential cation channel, subfamily C, member 3 |
| Alias Symbols |
TRP3, SCA41 |
| Peptide Sequence |
Synthetic peptide located within the following region: MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lof,C., (2008) J. Cell. Physiol. 216 (1), 245-252 |
| Description of Target |
TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC3 is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. TRPC3 may also be activated by internal calcium store depletion. |
| Protein Interactions |
STX3; TRPC1; PRKG1; ORAI1; PLCB1; PLCB2; TRPC6; NAPA; PLCB3; FKBP1A; VAMP2; SLC8A1; PRKCA; PLCG1; ITPR3; ITPR1; MX1; GNA11; CALM1; TRPC7; TRPC3; TRPC5; TRPC4; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TRPC3 (ARP58715_P050) antibody |
| Blocking Peptide |
For anti-TRPC3 (ARP58715_P050) antibody is Catalog # AAP58715 (Previous Catalog # AAPP35915) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the n terminal region of human TRPC3 |
| Uniprot ID |
Q13507 |
| Protein Name |
Short transient receptor potential channel 3 |
| Protein Accession # |
NP_003296 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003305 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
TRPC3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-TRPC3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Mouse brain
 | TRPC3 antibody - N-terminal region (ARP58715_P050) validated by WB using brainstem, Cerebellum, Thalamus, Hipppcampus, Cerebral Cortex |
|
| Image 3 | Human Heart
 | Rabbit Anti-TRPC3 antibody
Catalog Number: ARP58715
Formalin Fixed Paraffin Embedded Tissue: Human Heart
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec |
|
