FBXO27 Antibody - middle region (ARP58463_P050)

Data Sheet
 
Product Number ARP58463_P050
Product Page www.avivasysbio.com/fbxo27-antibody-middle-region-arp58463-p050.html
Name FBXO27 Antibody - middle region (ARP58463_P050)
Protein Size (# AA) 283 amino acids
Molecular Weight 31kDa
NCBI Gene Id 126433
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name F-box protein 27
Alias Symbols FBG5, Fbx27
Peptide Sequence Synthetic peptide located within the following region: LDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFVSFEHRGQDTQFWAG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Jin,J., (2004) Genes Dev. 18 (21), 2573-2580
Description of Target Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Protein Interactions CLN5; HSP90AA1; RBX1; CUL1; SKP1; ELAVL1; MGMT; STUB1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-FBXO27 (ARP58463_P050) antibody
Blocking Peptide For anti-FBXO27 (ARP58463_P050) antibody is Catalog # AAP58463 (Previous Catalog # AAPP34736)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FBXO27
Uniprot ID Q8NI29
Protein Name F-box only protein 27
Protein Accession # NP_849142
Purification Affinity Purified
Nucleotide Accession # NM_178820
Tested Species Reactivity Human
Gene Symbol FBXO27
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 83%
Image 1
Human Jurkat
WB Suggested Anti-FBXO27 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
 

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