ERLIN2 Antibody - middle region (ARP58461_P050)

• Product Number: ARP58461_P050
• Name: ERLIN2 Antibody - middle region (ARP58461_P050)
• Protein Size (# AA): 339 amino acids
• Molecular Weight: 38kDa
• NCBI Gene Id: 11160
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: ER lipid raft associated 2
• Alias Symbols: NET32, SPFH2, SPG18, C8orf2, Erlin-2
• Peptide Sequence: Synthetic peptide located within the following region: ASNSKIYFGKDIPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Pearce,M.M., (2007) J. Biol. Chem. 282 (28), 20104-20115
• Description of Target: ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is involved in ITPR1 degradation by the ERAD pathway.
• Protein Interactions: TIMM50; TMUB1; SRPRB; CCDC47; RHOT1; SEC61B; ERLIN1; HAX1; TRIM28; UBC; HSP90B1; TCP1; HSPA5; HSPA4; CSE1L; CASP8; CANX; ATP2A2; PSENEN; APH1A; NCSTN; SCAP; SREBF2; SREBF1; PSEN1; INSIG1; AMFR; PPP6R3; STK3; ADRA1D; ADRB2; HDAC11; CLN3; MMS19; UBL4A; FN1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-ERLIN2 (ARP58461_P050) antibody is Catalog # AAP58461 (Previous Catalog # AAPP34734)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ERLIN2
• Uniprot ID: O94905
• Protein Name: Erlin-2
• Publications:

  Zhang, Y. et al. Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells. Hum. Exp. Toxicol. 32, 797-806 (2013). 23338683

• Sample Type Confirmation:

  ERLIN2 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HEK293T

• Protein Accession #: NP_009106
• Purification: Affinity Purified
• Nucleotide Accession #: NM_007175
• Tested Species Reactivity: Human
• Gene Symbol: ERLIN2
• Predicted Species Reactivity: Human, Mouse, Rat, Pig, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 100%; Rat: 93%
• Image 1: Human 293T
  
  WB Suggested Anti-ERLIN2 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: 293T cell lysate.ERLIN2 is strongly supported by BioGPS gene expression data to be expressed in HEK293T
• Image 2: Human HeLa, AT3
  
  ERLIN2 antibody - middle region (ARP58461_P050) validated by WB using HeLa, aT3 cells at 1:200 / 1:1000.
• Image 3: Human 721_B
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Type: 721_B
  Antibody Dilution: 1.0ug/mlERLIN2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
• Image 4: Human Adult Placenta
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Type: Human Adult Placenta
  Antibody Dilution: 1.0ug/ml
• Image 5: Human Fetal Lung
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Type: Human Fetal Lung
  Antibody Dilution: 1.0ug/ml
• Image 6: Human Fetal Heart
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Type: Human Fetal Heart
  Antibody Dilution: 1.0ug/ml
• Image 7: Human Fetal Brain
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Type: Human Fetal Brain
  Antibody Dilution: 1.0ug/ml
• Image 8: Human HT1080 Whole Cell
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Tissue: Human HT1080 Whole Cell
  Antibody Dilution: 1ug/ml
• Image 9: Human HepG2 Whole Cell
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Tissue: Human HepG2 Whole Cell
  Antibody Dilution: 1ug/ml
• Image 10: Human HepG2 Whole Cell
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Tissue: Human HepG2 Whole Cell
  Antibody Dilution: 1ug/ml
• Image 11: Human MCF7 Whole Cell
  
  Host: Rabbit
  Target Name: ERLIN2
  Sample Tissue: Human MCF7 Whole Cell
  Antibody Dilution: 1ug/ml