| Product Number |
ARP58384_P050 |
| Product Page |
www.avivasysbio.com/evi1-antibody-n-terminal-region-arp58384-p050.html |
| Name |
EVI1 Antibody - N-terminal region (ARP58384_P050) |
| Protein Size (# AA) |
1051 amino acids |
| Molecular Weight |
118kDa |
| NCBI Gene Id |
2122 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MDS1 and EVI1 complex locus |
| Alias Symbols |
EVI1, MDS1, KMT8E, PRDM3, RUSAT2, MDS1-EVI1, AML1-EVI-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: VKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sato,T., (2008) Cancer Sci. 99 (7), 1407-1413 |
| Description of Target |
EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. |
| Protein Interactions |
PRMT1; PIAS4; SUMO1; SOX2; ELAVL1; SIRT1; KAT2B; SMAD4; SMAD3; SMAD2; SMAD1; EHMT2; SUV39H1; MECOM; HDAC1; HDAC4; CTBP2; CTBP1; CREBBP; MBD3; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MECOM (ARP58384_P050) antibody |
| Blocking Peptide |
For anti-MECOM (ARP58384_P050) antibody is Catalog # AAP58384 (Previous Catalog # AAPP33508) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EVI1 |
| Uniprot ID |
Q03112 |
| Protein Name |
MDS1 and EVI1 complex locus protein EVI1 |
| Protein Accession # |
NP_005232 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005241 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MECOM |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93% |
| Image 1 | Human HeLa
 | WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate |
|
| Image 2 | Human A549
 | WB Suggested Anti-EVI1 antibody Titration: 1 ug/mL
Sample Type: Human A549 |
|
