| Product Number |
ARP58338_P050 |
| Product Page |
www.avivasysbio.com/tinf2-antibody-middle-region-arp58338-p050.html |
| Name |
TINF2 Antibody - middle region (ARP58338_P050) |
| Protein Size (# AA) |
451 amino acids |
| Molecular Weight |
50kDa |
| NCBI Gene Id |
26277 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
TERF1 (TRF1)-interacting nuclear factor 2 |
| Alias Symbols |
TIN2, DKCA3 |
| Peptide Sequence |
Synthetic peptide located within the following region: SDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCR |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kim,S.H., (2008) J. Cell Biol. 181 (3), 447-460 |
| Description of Target |
TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly. |
| Protein Interactions |
ACD; TERF2; TPP1; ANXA8L1; TNKS; TERF1; VIPR1; ZNF790; PAGE2; TUBB; DHFRL1; APOBEC3F; REM2; NUDCD2; CCDC43; SCRN2; TRIM15; TXNDC17; AFAP1L2; FERMT3; KCTD17; ANKMY2; PPP6R3; PGM2; APPL2; BIN2; LGALSL; PHPT1; GNMT; OR2H1; CCDC9; POT1; AIPL1; NCDN; ACOT7; TO |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TINF2 (ARP58338_P050) antibody |
| Blocking Peptide |
For anti-TINF2 (ARP58338_P050) antibody is Catalog # AAP58338 (Previous Catalog # AAPP32948) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TINF2 |
| Uniprot ID |
Q9BSI4 |
| Protein Name |
TERF1-interacting nuclear factor 2 |
| Sample Type Confirmation |
TINF2 is supported by BioGPS gene expression data to be expressed in MCF7 |
| Protein Accession # |
NP_001092744 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001099274 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TINF2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 86%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 85% |
| Image 1 | Human MCF7
 | Host: Rabbit
Target Name: TINF2
Sample Type: MCF7
Antibody Dilution: 1.0ug/mlTINF2 is supported by BioGPS gene expression data to be expressed in MCF7 |
|
| Image 2 | Human MCF-7
 | WB Suggested Anti-TINF2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysateTINF2 is supported by BioGPS gene expression data to be expressed in MCF7 |
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