| Product Number |
ARP58203_P050 |
| Product Page |
www.avivasysbio.com/a2bp1-antibody-middle-region-arp58203-p050.html |
| Name |
A2BP1 Antibody - middle region (ARP58203_P050) |
| Protein Size (# AA) |
395 amino acids |
| Molecular Weight |
42kDa |
| NCBI Gene Id |
54715 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| Alias Symbols |
2BP1, FOX1, A2BP1, FOX-1, HRNBP1 |
| Peptide Sequence |
Synthetic peptide located within the following region: TAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Uhl,G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693 |
| Description of Target |
Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. |
| Protein Interactions |
C1orf94; RBPMS; PRR20A; HSFY1; RHOXF2; ALG13; RBFOX1; FAM168A; DAZAP2; MAGED1; BHLHE40; SNRPN; DAB1; CRX; UBC; HSFX1; RBM24; LZTS2; DMRTB1; PCBP4; NOC2L; GCA; RBFOX2; KIFAP3; CELF3; PSMF1; QKI; NUMBL; PRRC2A; ATXN2; ATXN1; HNRNPF; DVL2; ATN1; TNIP1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RBFOX1 (ARP58203_P050) antibody |
| Blocking Peptide |
For anti-RBFOX1 (ARP58203_P050) antibody is Catalog # AAP58203 (Previous Catalog # AAPP32802) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human A2BP1 |
| Uniprot ID |
Q9NWB1 |
| Protein Name |
RNA binding protein fox-1 homolog 1 |
| Protein Accession # |
NP_665900 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_145893 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RBFOX1 |
| Predicted Species Reactivity |
Human, Mouse, Cow, Dog, Horse, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Zebrafish: 100% |
| Image 1 | Human Brain
 | WB Suggested Anti-A2BP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human brain |
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