A2BP1 Antibody - N-terminal region (ARP58202_P050)

• Product Number: ARP58202_P050
• Name: A2BP1 Antibody - N-terminal region (ARP58202_P050)
• Protein Size (# AA): 370 amino acids
• Molecular Weight: 40kDa
• NCBI Gene Id: 54715
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: RNA binding protein, fox-1 homolog (C. elegans) 1
• Alias Symbols: 2BP1, FOX1, A2BP1, FOX-1, HRNBP1
• Peptide Sequence: Synthetic peptide located within the following region: NCEREQLRGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPE
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
• Protein Interactions: C1orf94; RBPMS; PRR20A; HSFY1; RHOXF2; ALG13; RBFOX1; FAM168A; DAZAP2; MAGED1; BHLHE40; SNRPN; DAB1; CRX; UBC; HSFX1; RBM24; LZTS2; DMRTB1; PCBP4; NOC2L; GCA; RBFOX2; KIFAP3; CELF3; PSMF1; QKI; NUMBL; PRRC2A; ATXN2; ATXN1; HNRNPF; DVL2; ATN1; TNIP1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-RBFOX1 (ARP58202_P050) antibody is Catalog # AAP58202
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human A2BP1
• Uniprot ID: Q9NWB1
• Protein Name: RNA binding protein fox-1 homolog 1
• Protein Accession #: NP_001135805
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001142333
• Tested Species Reactivity: Human
• Gene Symbol: RBFOX1
• Predicted Species Reactivity: Human, Mouse, Cow
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Human: 100%; Mouse: 100%
• Image 1: Human Brain, Human Placenta
  
  Host: Rabbit
  Target: RBFOX1
  Positive control (+): Human Brain (BR)
  Negative control (-): Human Placenta (PL)
  Antibody concentration: 1ug/ml
• Image 2: Human 293T
  
  Host: Rabbit
  Target Name: HIRIP3
  Sample Type: 293T
  Antibody Dilution: 1.0ug/ml
• Image 3: Human A549 Whole Cell
  
  Host: Rabbit
  Target Name: A2BP1
  Sample Type: A549 Whole Cell lysates
  Antibody Dilution: 1.0ug/ml