HOXA11 Antibody - middle region (ARP58161_P050)

• Product Number: ARP58161_P050
• Name: HOXA11 Antibody - middle region (ARP58161_P050)
• Protein Size (# AA): 313 amino acids
• Molecular Weight: 34kDa
• NCBI Gene Id: 3207
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Homeobox A11
• Alias Symbols: HOX1, HOX1I, RUSAT1
• Peptide Sequence: Synthetic peptide located within the following region: FETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSD
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Connell,K.A., (2008) J. Clin. Invest. 118 (3), 1050-1055
• Description of Target: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Protein Interactions: PGBD3; UBC; YY1; HDAC2; HDAC1; FOXO1; GMNN; MEIS1; CREBBP;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-HOXA11 (ARP58161_P050) antibody is Catalog # AAP58161 (Previous Catalog # AAPP32594)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA11
• Uniprot ID: P31270
• Protein Name: Homeobox protein Hox-A11
• Protein Accession #: NP_005514
• Purification: Affinity Purified
• Nucleotide Accession #: NM_005523
• Tested Species Reactivity: Human
• Gene Symbol: HOXA11
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 100%; Rat: 92%
• Image 1: Transfected 293T
  
  WB Suggested Anti-HOXA11 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: Transfected 293T