| Product Number |
ARP58134_P050 |
| Product Page |
www.avivasysbio.com/ash2l-antibody-n-terminal-region-arp58134-p050.html |
| Name |
ASH2L Antibody - N-terminal region (ARP58134_P050) |
| Protein Size (# AA) |
628 amino acids |
| Molecular Weight |
69kDa |
| Subunit |
ASH2 |
| NCBI Gene Id |
9070 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Ash2 (absent, small, or homeotic)-like (Drosophila) |
| Alias Symbols |
ASH2, Bre2, ASH2L1, ASH2L2 |
| Peptide Sequence |
Synthetic peptide located within the following region: AAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Goei,V.L., (2008) Cancer Res. 68 (3), 749-758 |
| Description of Target |
ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. It may function as a transcriptional regulator and play a role in hematopoiesis. |
| Protein Interactions |
CXXC1; DPY30; SETD1A; RBBP5; PPARG; KMT2A; KMT2D; UBC; SENP3; KDM6A; PPP1CC; SMAD9; KDM6B; WWP1; BRCA1; BARD1; WDR5; MEN1; USF1; KMT2C; HCFC2; SETD1B; KDM4B; KMT2B; HCFC1; ESR1; CDC73; HIST3H3; PYGO2; WDR82; PSMC5; PRMT1; E2F4; E2F1; PAGR1; NCOA6; PAXIP1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ASH2L (ARP58134_P050) antibody |
| Blocking Peptide |
For anti-ASH2L (ARP58134_P050) antibody is Catalog # AAP58134 (Previous Catalog # AAPP32567) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ASH2L |
| Uniprot ID |
Q9UBL3 |
| Protein Name |
Set1/Ash2 histone methyltransferase complex subunit ASH2 |
| Protein Accession # |
NP_004665 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004674 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ASH2L |
| Predicted Species Reactivity |
Human, Mouse, Dog, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 85%; Horse: 85%; Human: 100%; Mouse: 85% |
| Image 1 | Human HeLa
 | WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate |
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