| Product Number |
ARP58066_P050 |
| Product Page |
www.avivasysbio.com/rb1-antibody-middle-region-arp58066-p050.html |
| Name |
RB1 Antibody - middle region (ARP58066_P050) |
| Protein Size (# AA) |
928 amino acids |
| Molecular Weight |
106kDa |
| NCBI Gene Id |
5925 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Retinoblastoma 1 |
| Alias Symbols |
RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1 |
| Peptide Sequence |
Synthetic peptide located within the following region: AEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophospho |
| Protein Interactions |
RAF1; E2F1; ABL1; HDAC1; KDM2A; SMARCA4; USP7; UBC; DYRK1A; NEFM; DYRK1B; MAGEA11; ENC1; PPP1CA; CDKN1C; CDKN1A; CDK6; CDK4; CDK2; CCNE1; CCNA2; CCND1; HDAC11; PAX5; HIF1A; E2F4; CEBPE; CCNA1; SUMO1; UBE2I; TFAP2A; CDK3; CDK1; CCNC; CCNB1; MRPS18B; SUMO2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RB1 (ARP58066_P050) antibody |
| Blocking Peptide |
For anti-RB1 (ARP58066_P050) antibody is Catalog # AAP58066 (Previous Catalog # AAPP32489) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RB1 |
| Uniprot ID |
P06400 |
| Protein Name |
Retinoblastoma-associated protein |
| Protein Accession # |
NP_000312 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000321 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100% |
| Image 1 | Human THP-1
 | WB Suggested Anti-RB1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: THP-1 cell lysate |
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