| Product Number |
ARP58007_P050 |
| Product Page |
www.avivasysbio.com/gtf2i-antibody-middle-region-arp58007-p050.html |
| Name |
GTF2I Antibody - middle region (ARP58007_P050) |
| Protein Size (# AA) |
998 amino acids |
| Molecular Weight |
112kDa |
| NCBI Gene Id |
2969 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
General transcription factor IIi |
| Alias Symbols |
WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I |
| Peptide Sequence |
Synthetic peptide located within the following region: INNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) |
| Description of Target |
GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene. |
| Protein Interactions |
TP53; ZMYM3; PIAS2; TUBG1; TRAF6; SUMO2; SUMO3; AP2B1; DPY30; GCC1; MTUS2; MDM2; UBC; SUMO1; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; CTPS2; WARS; RPL28; RAD23B; PRPS2; PRKDC; NUCB1; METTL1; ADSL; FBXO6; UBD; CBX2; TAB2; AP4S1; CBX4; MAPK12; C4BPA; MAP3K3; SLU |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GTF2I (ARP58007_P050) antibody |
| Blocking Peptide |
For anti-GTF2I (ARP58007_P050) antibody is Catalog # AAP58007 (Previous Catalog # AAPP32430) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human GTF2I |
| Uniprot ID |
P78347 |
| Protein Name |
General transcription factor II-I |
| Sample Type Confirmation |
There is BioGPS gene expression data showing that GTF2I is expressed in HEK293T |
| Protein Accession # |
NP_127492 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_032999 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
GTF2I |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100% |
| Image 1 | Human 293T
 | WB Suggested Anti-GTF2I Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysateThere is BioGPS gene expression data showing that GTF2I is expressed in HEK293T |
|
| Image 2 | Human heart
 | Rabbit Anti-GTF2I Antibody
Catalog Number: ARP58007_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 3 | Mouse Testis
 | Host: Mouse
Target Name: GTF2I
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml |
|
