MATN2 Antibody - middle region (ARP57667_P050)

Data Sheet
 
Product Number ARP57667_P050
Product Page www.avivasysbio.com/matn2-antibody-middle-region-arp57667-p050.html
Name MATN2 Antibody - middle region (ARP57667_P050)
Protein Size (# AA) 937 amino acids
Molecular Weight 107 kDa
NCBI Gene Id 4147
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Matrilin 2
Description
Alias Symbols -
Peptide Sequence Synthetic peptide located within the following region: AVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKLKKGICEALED
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Ichikawa,T., (2008) Biochem. Biophys. Res. Commun. 369 (4), 994-1000
Description of Target MATN2 is a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined.This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interactions DVL3; CBFA2T3; ATXN1L; ATXN1; ATXN7; CACNA1A; MATN4; MATN2; COL4A6; COL4A5; FN1; FBN2; COL1A1; COL4A4; COL4A1; COL4A2; COL4A3; MATN1; MATN3;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-MATN2 (ARP57667_P050) antibody
Blocking Peptide For anti-MATN2 (ARP57667_P050) antibody is Catalog # AAP57667 (Previous Catalog # AAPP35443)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MATN2
Uniprot ID A8K106
Protein Name Matrilin-2
Publications

Extracellular matrix changes in corneal opacification vary depending on etiology. Mol Vis. 27, 26-36 (2021). 33633437

Szalai, E. et al. Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol. Vis. 18, 1927-36 (2012). 22876117

Protein Accession # NP_085072
Purification Affinity Purified
Nucleotide Accession # NM_030583
Tested Species Reactivity Human
Gene Symbol MATN2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 91%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 82%
Image 1
Human Lung
WB Suggested Anti-MATN2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Lung
Image 2

25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 1ug/mL of the antibody was used in this experiment.
 

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