| Product Number |
ARP57429_P050 |
| Product Page |
www.avivasysbio.com/peli1-antibody-n-terminal-region-arp57429-p050.html |
| Name |
PELI1 Antibody - N-terminal region (ARP57429_P050) |
| Protein Size (# AA) |
418 amino acids |
| Molecular Weight |
46kDa |
| NCBI Gene Id |
57162 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Pellino E3 ubiquitin protein ligase 1 |
| Alias Symbols |
DKFZp686C18116, MGC50990 |
| Peptide Sequence |
Synthetic peptide located within the following region: ESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1. |
| Protein Interactions |
UBC; VAC14; TRIP13; BCL6; SRPK2; SRPK1; DEAF1; IRAK1; UBE2V1; UBE2N; UBE2D2; UBE2D1; IRAK4; TRAF6; NR2C2; MYD88; SMAD6; IL1R1; TBK1; IKBKB; UBE2I; RIPK1; IRAK2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PELI1 (ARP57429_P050) antibody |
| Blocking Peptide |
For anti-PELI1 (ARP57429_P050) antibody is Catalog # AAP57429 (Previous Catalog # AAPP41426) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1 |
| Uniprot ID |
Q8C669 |
| Protein Name |
E3 ubiquitin-protein ligase pellino homolog 1 |
| Sample Type Confirmation |
PELI1 is supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_065702 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_020651 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PELI1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human 721_B
 | Host: Rabbit
Target Name: PELI1
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlPELI1 is supported by BioGPS gene expression data to be expressed in 721_B |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-PELI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
