CENPN Antibody - middle region (ARP57258_P050)

Data Sheet
 
Product Number ARP57258_P050
Product Page www.avivasysbio.com/cenpn-antibody-middle-region-arp57258-p050.html
Name CENPN Antibody - middle region (ARP57258_P050)
Protein Size (# AA) 353 amino acids
Molecular Weight 40 kDa
NCBI Gene Id 55839
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Centromere protein N
Alias Symbols BM039, CENP-N, ICEN32, C16orf60
Peptide Sequence Synthetic peptide located within the following region: SFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPN is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
Protein Interactions UBC; CENPP; CENPL; CENPU; CENPO; CENPM; CENPH; CENPK; CENPN; CENPQ; CENPI; CENPA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
WBY
SPR
YCHAROS
Datasheets/Manuals Printable datasheet for anti-CENPN (ARP57258_P050) antibody
Blocking Peptide For anti-CENPN (ARP57258_P050) antibody is Catalog # AAP57258 (Previous Catalog # AAPP44233)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CENPN
Uniprot ID Q96H22
Sample Type Confirmation

CENPN is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_001094095
Purification Affinity Purified
Nucleotide Accession # NM_001100625
Tested Species Reactivity Human
Gene Symbol CENPN
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Application IF, WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 79%
Image 1
DNA/ACA
Sample Type : DNA/ACA
Image 2
Human Jurkat
WB Suggested Anti-CENPN Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateCENPN is supported by BioGPS gene expression data to be expressed in Jurkat
Image 3
Huh-7
Sample Type:
Huh-7
Primary Antibody Dilution:
4 ug/ml
Secondary Antibody:
Anti-rabbit Alexa 546
Secondary Antibody Dilution:
2 ug/ml
Gene Name:
CENPN
Image 4
MCF7
Sample Type:
MCF7
Primary Antibody Dilution:
4 ug/ml
Secondary Antibody:
Anti-rabbit Alexa 546
Secondary Antibody Dilution:
2 ug/ml
Gene Name:
CENPN
 

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