| Product Number |
ARP56609_P050 |
| Product Page |
www.avivasysbio.com/ndufs1-antibody-middle-region-arp56609-p050.html |
| Name |
NDUFS1 Antibody - middle region (ARP56609_P050) |
| Protein Size (# AA) |
727 amino acids |
| Molecular Weight |
79 kDa |
| Subunit |
mitochondrial |
| NCBI Gene Id |
4719 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
| Alias Symbols |
CI-75k, MC1DN5, CI-75Kd, PRO1304 |
| Peptide Sequence |
Synthetic peptide located within the following region: TPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDIE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. |
| Protein Interactions |
SUMO2; HSFY1; UBC; MDM2; RNF2; KDM1A; FBXO6; VCAM1; BTK; Htt; NDUFS7; RHOT2; NDUFA12; TMEM126B; MRPL13; STX12; SEC24C; SDHB; RPL27; RAB5B; OPA1; NDUFV3; NDUFV2; NDUFS8; NDUFV1; NDUFS2; NDUFB10; NDUFB9; NDUFB5; NDUFA9; CPT1A; ATP5C1; ATP5B; CUL3; SIRT7; MY |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NDUFS1 (ARP56609_P050) antibody |
| Blocking Peptide |
For anti-NDUFS1 (ARP56609_P050) antibody is Catalog # AAP56609 (Previous Catalog # AAPP39316) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NDUFS1 |
| Uniprot ID |
P28331 |
| Protein Name |
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
| Protein Accession # |
NP_004997 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005006 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NDUFS1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79% |
| Image 1 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by acetylation.
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