| Product Number |
ARP56095_P050 |
| Product Page |
https://www.avivasysbio.com/ppox-antibody-n-terminal-region-arp56095-p050.html |
| Name |
PPOX Antibody - N-terminal region (ARP56095_P050) |
| Protein Size (# AA) |
477 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
5498 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Protoporphyrinogen oxidase |
| Alias Symbols |
VP, PPO, V290M |
| Peptide Sequence |
Synthetic peptide located within the following region: SSERLGGWIRSVRGPNGAIFELGPRGIRPAGALGARTLLLVSELGLDSEV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
de Gene 409 (1-2), 83-91 (2008) |
| Description of Target |
PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. |
| Protein Interactions |
HNRNPD; UBC; COPS5; HAP1; PPOX; IMMT; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PPOX (ARP56095_P050) antibody |
| Blocking Peptide |
For anti-PPOX (ARP56095_P050) antibody is Catalog # AAP56095 (Previous Catalog # AAPP37716) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX |
| Uniprot ID |
P50336 |
| Protein Name |
Protoporphyrinogen oxidase |
| Protein Accession # |
NP_000300 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000309 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PPOX |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HT1080
 | WB Suggested Anti-PPOX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysate |
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