VASH1 Antibody - N-terminal region (ARP55099_P050)

Data Sheet
 
Product Number ARP55099_P050
Product Page www.avivasysbio.com/vash1-antibody-n-terminal-region-arp55099-p050.html
Name VASH1 Antibody - N-terminal region (ARP55099_P050)
Protein Size (# AA) 365 amino acids
Molecular Weight 41kDa
NCBI Gene Id 22846
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Vasohibin 1
Alias Symbols TTCP 1, KIAA1036
Peptide Sequence Synthetic peptide located within the following region: ATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPER
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Yoshinaga,K., (2008) Cancer Sci. 99 (5), 914-919
Description of Target VASH1 is the angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. VASH1 does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. It acts in an autocrine manner. VASH1 inhibits artery neointimal formation and macrophage infiltration. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Protein Interactions DHPS; CCDC23;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-VASH1 (ARP55099_P050) antibody
Blocking Peptide For anti-VASH1 (ARP55099_P050) antibody is Catalog # AAP55099 (Previous Catalog # AAPP32717)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human VASH1
Uniprot ID Q7L8A9
Protein Name Vasohibin-1
Protein Accession # NP_055724
Purification Affinity Purified
Nucleotide Accession # NM_014909
Tested Species Reactivity Human
Gene Symbol VASH1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
Image 1
Human 721_B
WB Suggested Anti-VASH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
 

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