Product Number |
ARP54776_P050-HRP |
Product Page |
www.avivasysbio.com/ldha-antibody-n-terminal-region-hrp-arp54776-p050-hrp.html |
Name |
LDHA Antibody - N-terminal region : HRP (ARP54776_P050-HRP) |
Protein Size (# AA) |
332 amino acids |
Molecular Weight |
37kDa |
Conjugation |
HRP: Horseradish Peroxidase |
NCBI Gene Id |
3939 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
lactate dehydrogenase A |
Alias Symbols |
LDHM, GSD11, PIG19, HEL-S-133P |
Peptide Sequence |
Synthetic peptide located within the following region: ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALV |
Product Format |
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
Reference |
Listerman,I., PLoS Genet. 3 (11), E212 (2007) |
Description of Target |
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. |
Protein Interactions |
MAPK10; LDHB; FUS; HUWE1; ISG15; UBC; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; ASB9; RNF2; CNDP2; NAGK; C11orf58; NDRG1; BZW1; KYNU; TCEA1; SORD; SMS; RPS6KA1; PGD; PAFAH1B3; GSR; PDIA3; GNAI3; DLD; CSE1L; LDHAL6B; FTO; BCCIP; XRN1; FBXO6; UPF2; YWHAQ; METT |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-LDHA (ARP54776_P050-HRP) antibody |
Additional Information |
IHC Information: Paraffin embedded liver tissue, tested with an antibody dilution of 2.5 ug/ml. |
Blocking Peptide |
For anti-LDHA (ARP54776_P050-HRP) antibody is Catalog # AAP54776 (Previous Catalog # AAPP31571) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human LDHA |
Uniprot ID |
P00338 |
Protein Name |
L-lactate dehydrogenase A chain |
Protein Accession # |
NP_005557 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005566 |
Gene Symbol |
LDHA |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Goat: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 93%; Sheep: 86% |
Image 1 | |