LDHA Antibody - N-terminal region : HRP (ARP54776_P050-HRP)

Data Sheet
 
Product Number ARP54776_P050-HRP
Product Page www.avivasysbio.com/ldha-antibody-n-terminal-region-hrp-arp54776-p050-hrp.html
Name LDHA Antibody - N-terminal region : HRP (ARP54776_P050-HRP)
Protein Size (# AA) 332 amino acids
Molecular Weight 37kDa
Conjugation HRP: Horseradish Peroxidase
NCBI Gene Id 3939
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name lactate dehydrogenase A
Alias Symbols LDHM, GSD11, PIG19, HEL-S-133P
Peptide Sequence Synthetic peptide located within the following region: ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALV
Product Format Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reference Listerman,I., PLoS Genet. 3 (11), E212 (2007)
Description of Target The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Protein Interactions MAPK10; LDHB; FUS; HUWE1; ISG15; UBC; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; ASB9; RNF2; CNDP2; NAGK; C11orf58; NDRG1; BZW1; KYNU; TCEA1; SORD; SMS; RPS6KA1; PGD; PAFAH1B3; GSR; PDIA3; GNAI3; DLD; CSE1L; LDHAL6B; FTO; BCCIP; XRN1; FBXO6; UPF2; YWHAQ; METT
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-LDHA (ARP54776_P050-HRP) antibody
Additional Information IHC Information: Paraffin embedded liver tissue, tested with an antibody dilution of 2.5 ug/ml.
Blocking Peptide For anti-LDHA (ARP54776_P050-HRP) antibody is Catalog # AAP54776 (Previous Catalog # AAPP31571)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LDHA
Uniprot ID P00338
Protein Name L-lactate dehydrogenase A chain
Protein Accession # NP_005557
Purification Affinity Purified
Nucleotide Accession # NM_005566
Gene Symbol LDHA
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 86%; Goat: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 93%; Sheep: 86%
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