Product Number |
ARP54614_P050 |
Product Page |
www.avivasysbio.com/flii-antibody-middle-region-arp54614-p050.html |
Name |
FLII Antibody - middle region (ARP54614_P050) |
Protein Size (# AA) |
1269 amino acids |
Molecular Weight |
145kDa |
NCBI Gene Id |
2314 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Flightless I homolog (Drosophila) |
Alias Symbols |
FLI, FLIL, Fli1 |
Peptide Sequence |
Synthetic peptide located within the following region: LAEDILNTMFDTSYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
Description of Target |
FLII is a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This gene is located within the Smith-Magenis syndrome region on chromosome 17.This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
UBC; SUMO2; C14orf166; RTCB; IGF2BP3; PDCD6; LRRFIP1; EIF2B3; RPL27; RFC4; RFC2; PRKDC; NMT1; HNRNPM; MRE11A; KRT18; DHX9; DDX1; PAN2; HSP90AA1; FMNL1; BRCA1; EIF1AX; DGCR8; FBXO25; LRRFIP2; MYD88; ESR1; ACTL6A; GRIP1; CARM1; TRAIP; PRMT1; OPTN; DLST; ACT |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-FLII (ARP54614_P050) antibody |
Blocking Peptide |
For anti-FLII (ARP54614_P050) antibody is Catalog # AAP54614 (Previous Catalog # AAPP31405) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human FLII |
Uniprot ID |
Q13045 |
Protein Name |
Protein flightless-1 homolog |
Protein Accession # |
NP_002009 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_002018 |
Tested Species Reactivity |
Human |
Gene Symbol |
FLII |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79% |
Image 1 | Human OVCAR-3
| WB Suggested Anti-FLII Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: OVCAR-3 cell lysate |
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Image 2 | Human Bronchial Epithelial Tissue
| FLII antibody - middle region (ARP54614_P050)
Catalog Number: ARP54614_P050
Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue
Observed Staining: Cytoplasm and membrane of bronchial epithelial tissue
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
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