FGR Antibody - middle region (ARP54523_P050)

• Product Number: ARP54523_P050
• Name: FGR Antibody - middle region (ARP54523_P050)
• Protein Size (# AA): 529 amino acids
• Molecular Weight: 59kDa
• NCBI Gene Id: 2268
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
• Alias Symbols: SRC2, c-fgr, c-src2, p55-Fgr, p58-Fgr, p55c-fgr, p58c-fgr
• Peptide Sequence: Synthetic peptide located within the following region: CPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQ
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Protein Interactions: IKBKG; STAT3; HSP90AA1; ERBB2; NR1I2; UBC; DOK1; KHDRBS1; SYK; SH3KBP1; FASLG; INPP5D; SLAMF1; VDR; HCLS1; CCR3; DAB2; PTK2; CD24; WAS; SRC; CBL; FGR; SNCA; YWHAQ; CSK; ARRB1; NCOA6;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-FGR (ARP54523_P050) antibody is Catalog # AAP54523 (Previous Catalog # AAPP41704)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGR
• Uniprot ID: P09769
• Protein Name: Tyrosine-protein kinase Fgr
• Protein Accession #: NP_001036194
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001042729
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: FGR
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 93%; Guinea Pig: 83%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 92%; Rat: 93%; Zebrafish: 83%
• Image 1: Human U937
  
  WB Suggested Anti-FGR Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:1562500
  Positive Control: U937 cell lysate
• Image 2: Mouse Heart
  
  Host: Mouse
  Target Name: FGR
  Sample Tissue: Mouse Heart
  Antibody Dilution: 1ug/ml