CDKN3 Antibody - C-terminal region (ARP53629_P050)

Data Sheet
 
Product Number ARP53629_P050
Product Page https://www.avivasysbio.com/cdkn3-antibody-c-terminal-region-arp53629-p050.html
Name CDKN3 Antibody - C-terminal region (ARP53629_P050)
Protein Size (# AA) 212 amino acids
Molecular Weight 23kDa
NCBI Gene Id 1033
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Cyclin-dependent kinase inhibitor 3
Alias Symbols KAP, CDI1, CIP2, KAP1
Peptide Sequence Synthetic peptide located within the following region: CKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Okamoto,K., (2006) Biochem. Biophys. Res. Commun. 351 (1), 216-222
Description of Target CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions CDK2; UBC; NCOA3; MS4A3; CDKN3; CDK3; CDC25A; CDK1; CEBPA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CDKN3 (ARP53629_P050) antibody
Blocking Peptide For anti-CDKN3 (ARP53629_P050) antibody is Catalog # AAP53629 (Previous Catalog # AAPP30469)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CDKN3
Uniprot ID Q16667
Protein Name Cyclin-dependent kinase inhibitor 3
Protein Accession # NP_005183
Purification Affinity Purified
Nucleotide Accession # NM_005192
Tested Species Reactivity Human
Gene Symbol CDKN3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 92%
Image 1
Human Lung
WB Suggested Anti-CDKN3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung