DNALI1 Antibody - N-terminal region (ARP53611_P050)

Data Sheet
 
Product Number ARP53611_P050
Product Page www.avivasysbio.com/dnali1-antibody-n-terminal-region-arp53611-p050.html
Name DNALI1 Antibody - N-terminal region (ARP53611_P050)
Protein Size (# AA) 280 amino acids
Molecular Weight 31kDa
NCBI Gene Id 7802
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Dynein, axonemal, light intermediate chain 1
Alias Symbols P28, hp28, dJ423B22.5
Peptide Sequence Synthetic peptide located within the following region: MVTANKAHTGQGSCWVATLASAMIPPADSLLKYDTPVLVSRNTEKRSPKA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Combs,J., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14883-14888
Description of Target DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Protein Interactions SIAH1; PRMT6; APP; DNALI1; HTT; ABCF3; EPS8;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-DNALI1 (ARP53611_P050) antibody
Blocking Peptide For anti-DNALI1 (ARP53611_P050) antibody is Catalog # AAP53611 (Previous Catalog # AAPP30451)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DNALI1
Uniprot ID O14645
Protein Name Axonemal dynein light intermediate polypeptide 1
Protein Accession # NP_003453
Purification Affinity Purified
Nucleotide Accession # NM_003462
Tested Species Reactivity Human
Gene Symbol DNALI1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human nasal epithelial
Application: IHC
Species+tissue/cell type:Human nasal epithelial cells
Primary antibody dilution: 1:1000
Secondary antibody: Goat anti-rabbit Alexa Fluor 546
Secondary antibody dilution:1:1000 - See more at: http://www.avivasysbio.com/dnali1-antibody-n-terminal-region-arp53611-p050.html#sthash.SFTiXW2a.dpuf
Image 2
Transfected 293T
WB Suggested Anti-DNALI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
 

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