CPD Antibody - N-terminal region (ARP53585_P050)

Data Sheet
 
Product Number ARP53585_P050
Product Page www.avivasysbio.com/cpd-antibody-n-terminal-region-arp53585-p050.html
Name CPD Antibody - N-terminal region (ARP53585_P050)
Protein Size (# AA) 1380 amino acids
Molecular Weight 152kDa
NCBI Gene Id 1362
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Carboxypeptidase D
Alias Symbols GP180
Peptide Sequence Synthetic peptide located within the following region: SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPP
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Hoff,N.P., (2007) J. Clin. Immunol. 27 (6), 568-579
Description of Target The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D (CPD) has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions UBC; LGR4; ASB17; FBXO6; ATP4A; AATF; UBL4A; RAD18; KIAA0368; TCF3; ELAVL1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CPD (ARP53585_P050) antibody
Blocking Peptide For anti-CPD (ARP53585_P050) antibody is Catalog # AAP53585 (Previous Catalog # AAPS33001)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CPD
Uniprot ID O75976
Protein Name Carboxypeptidase D
Protein Accession # NP_001295
Purification Affinity Purified
Nucleotide Accession # NM_001304
Tested Species Reactivity Human
Gene Symbol CPD
Predicted Species Reactivity Human, Mouse, Rat, Dog, Horse, Pig, Rabbit
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Dog: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 93%; Rat: 79%
Image 1
Human HeLa
WB Suggested Anti-CPD Antibody Titration: 0.2-1 ug/ml
Positive Control: Hela cell lysate
Image 2
Human Pineal Tissue
CPD antibody - N-terminal region (ARP53585_P050)
Catalog Number: ARP53585_P050
Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue
Observed Staining: Cytoplasm in pinealocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Image 3
Human THP-1 Whole Cell
Host: Rabbit
Target Name: CPD
Sample Tissue: Human THP-1 Whole Cell
Antibody Dilution: 0.2ug/ml
 

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