Product Number |
ARP53585_P050 |
Product Page |
www.avivasysbio.com/cpd-antibody-n-terminal-region-arp53585-p050.html |
Name |
CPD Antibody - N-terminal region (ARP53585_P050) |
Protein Size (# AA) |
1380 amino acids |
Molecular Weight |
152kDa |
NCBI Gene Id |
1362 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Carboxypeptidase D |
Alias Symbols |
GP180 |
Peptide Sequence |
Synthetic peptide located within the following region: SLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hoff,N.P., (2007) J. Clin. Immunol. 27 (6), 568-579 |
Description of Target |
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D (CPD) has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
UBC; LGR4; ASB17; FBXO6; ATP4A; AATF; UBL4A; RAD18; KIAA0368; TCF3; ELAVL1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CPD (ARP53585_P050) antibody |
Blocking Peptide |
For anti-CPD (ARP53585_P050) antibody is Catalog # AAP53585 (Previous Catalog # AAPS33001) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CPD |
Uniprot ID |
O75976 |
Protein Name |
Carboxypeptidase D |
Protein Accession # |
NP_001295 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001304 |
Tested Species Reactivity |
Human |
Gene Symbol |
CPD |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Dog: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 93%; Rat: 79% |
Image 1 | Human HeLa
| WB Suggested Anti-CPD Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cell lysate |
|
Image 2 | Human Pineal Tissue
| CPD antibody - N-terminal region (ARP53585_P050)
Catalog Number: ARP53585_P050
Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue
Observed Staining: Cytoplasm in pinealocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
Image 3 | Human THP-1 Whole Cell
| Host: Rabbit Target Name: CPD Sample Tissue: Human THP-1 Whole Cell Antibody Dilution: 0.2ug/ml |
|