| Product Number |
ARP52371_P050 |
| Product Page |
www.avivasysbio.com/copb1-antibody-middle-region-arp52371-p050.html |
| Name |
COPB1 Antibody - middle region (ARP52371_P050) |
| Protein Size (# AA) |
953 amino acids |
| Molecular Weight |
107kDa |
| Subunit |
beta |
| NCBI Gene Id |
1315 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Coatomer protein complex, subunit beta 1 |
| Alias Symbols |
COPB, BARMACS |
| Peptide Sequence |
Synthetic peptide located within the following region: QLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Goryachev,A.B. PLoS Comput. Biol. 2 (12), E172 (2006) |
| Description of Target |
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. |
| Protein Interactions |
SUMO2; NUDCD1; UBC; RNF2; EZH2; KLC1; DIAPH1; ARCN1; ACACA; COPG1; COPZ1; TLE3; FBXO6; UBD; KCNK3; KCNK9; NPM1; HDAC10; ERBB2IP; SNTA1; LZTS2; VPS18; NUB1; SERTAD1; FOXB1; IRAK3; TANK; ID1; HLA-DPB1; GRB2; XRCC6; FN1; CFTR; FMNL1; COPG2; COPE; COPB2; COPA |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-COPB1 (ARP52371_P050) antibody |
| Blocking Peptide |
For anti-COPB1 (ARP52371_P050) antibody is Catalog # AAP52371 (Previous Catalog # AAPP14315) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human COPB1 |
| Uniprot ID |
P53618 |
| Protein Name |
Coatomer subunit beta |
| Protein Accession # |
NP_057535 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_016451 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
COPB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human Liver
 | WB Suggested Anti-COPB1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver |
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