| Product Number |
ARP52217_P050 |
| Product Page |
www.avivasysbio.com/hsph1-antibody-middle-region-arp52217-p050.html |
| Name |
HSPH1 Antibody - middle region (ARP52217_P050) |
| Protein Size (# AA) |
858 amino acids |
| Molecular Weight |
97kDa |
| NCBI Gene Id |
10808 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Heat shock 105kDa/110kDa protein 1 |
| Alias Symbols |
HSP105, HSP105A, HSP105B, NY-CO-25 |
| Peptide Sequence |
Synthetic peptide located within the following region: EENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Meares,G.P., (2008) Cell. Signal. 20 (2), 347-358 |
| Description of Target |
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities. |
| Protein Interactions |
HUWE1; UBC; SUMO2; SUMO3; HSPA8; MDM2; ILK; SET; PPM1G; PLOD2; HSPA4; DPYSL2; CTNNA1; PARVA; PUS7; SAMHD1; XPO7; FAF1; CARM1; SEC23A; PRMT3; FARSB; RANBP3; HIRIP3; HIST1H4A; USP11; SF1; UGP2; HECW2; FBXO6; TARDBP; CFTR; METTL21A; env; NOS2; HSP90AB1; HSP9 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-HSPH1 (ARP52217_P050) antibody |
| Blocking Peptide |
For anti-HSPH1 (ARP52217_P050) antibody is Catalog # AAP52217 (Previous Catalog # AAPY03639) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human HSPH1 |
| Uniprot ID |
Q92598 |
| Protein Name |
Heat shock protein 105 kDa |
| Publications |
Expression and function of HSP110 family in mouse testis after vasectomy. Asian J. Androl. (2016). 26952955 |
| Sample Type Confirmation |
HSPH1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, MCF7 |
| Protein Accession # |
NP_006635 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006644 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HSPH1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human 293T
 | WB Suggested Anti-HSPH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate |
|
| Image 2 | Human 721_B
 | Host: Rabbit
Target Name: HSPH1
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlHSPH1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
|
| Image 3 | Human MCF7
 | Host: Rabbit
Target Name: HSPH1
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlHSPH1 is strongly supported by BioGPS gene expression data to be expressed in MCF7 |
|
| Image 4 | Human Fetal Brain
 | Host: Rabbit
Target Name: HSPH1
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml |
|
| Image 5 | Human liver tissue
 | Rabbit Anti-HSPH1 Antibody
Catalog Number: ARP52217_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in endothelial cells in sinusoids
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
