SSX2 Antibody - middle region : Biotin (ARP51721_P050-Biotin)

Data Sheet
 
Product Number ARP51721_P050-Biotin
Product Page www.avivasysbio.com/ssx2-antibody-middle-region-biotin-arp51721-p050-biotin.html
Name SSX2 Antibody - middle region : Biotin (ARP51721_P050-Biotin)
Protein Size (# AA) 223 amino acids
Molecular Weight 24kDa
Conjugation Biotin
NCBI Gene Id 6757
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40
Peptide Sequence Synthetic peptide located within the following region: TFGRLQGISPKIMPKKPAEEG
NDSEEVPEASGPQNDGKELCPPGKPTTS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein Interactions KRT40; SSX2IP; RAB3IP; SYCE1; ZMIZ2; MAGEC2; AKAP9; ZBED1; TAX1BP1; BLZF1; SUZ12; EED; SMARCA5; TLE1; SMARCA2; HDAC2; HDAC1; EZH2; ATF2; RNF2;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-SSX2 (ARP51721_P050-Biotin) antibody
Blocking Peptide For anti-SSX2 (ARP51721_P050-Biotin) antibody is Catalog # AAP51721
Immunogen The immunogen is a synthetic peptide directed towards the middle region of Human SSX2
Uniprot ID Q16385-2
Protein Name Protein SSX2
Protein Accession # NP_783629
Purification Affinity Purified
Nucleotide Accession # NM_175698
Gene Symbol SSX2
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%
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