NTRK2 Antibody - C-terminal region (ARP51316_P050)

Data Sheet
 
Product Number ARP51316_P050
Product Page www.avivasysbio.com/ntrk2-antibody-c-terminal-region-arp51316-p050.html
Name NTRK2 Antibody - C-terminal region (ARP51316_P050)
Protein Size (# AA) 553 amino acids
Molecular Weight 57kDa
NCBI Gene Id 4915
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Neurotrophic tyrosine kinase, receptor, type 2
Alias Symbols OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB
Peptide Sequence Synthetic peptide located within the following region: DFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Protein Interactions TNK2; RANBP9; POLR2G; HSP90AA1; AP1B1; NMNAT1; UBC; NTF4; Nedd4; SHC2; KIDINS220; DOK5; SH2B2; SH2B1; SHC3; RASGRF1; UBB; FRS3; GIPC1; NCK2; DYNLL1; SQSTM1; SHC1; NCK1; NTRK2; PTPN1; PTPN11; PLCG1; NTF3; NGFR; FYN; BDNF; TRAF6; PIK3R1; FRS2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NTRK2 (ARP51316_P050) antibody
Blocking Peptide For anti-NTRK2 (ARP51316_P050) antibody is Catalog # AAP51316 (Previous Catalog # AAPP46572)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2
Uniprot ID Q8WXJ5
Protein Name BDNF/NT-3 growth factors receptor
Protein Accession # NP_001018075
Purification Affinity Purified
Nucleotide Accession # NM_001018065
Tested Species Reactivity Human, Mouse
Gene Symbol NTRK2
Predicted Species Reactivity Human, Rat, Cow, Horse, Rabbit
Application IF, WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 88%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
Image 1
Mouse brain
Mouse brain
Image 2
Human heart
WB Suggested Anti-NTRK2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human heart
 

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