Product Number |
ARP51316_P050 |
Product Page |
www.avivasysbio.com/ntrk2-antibody-c-terminal-region-arp51316-p050.html |
Name |
NTRK2 Antibody - C-terminal region (ARP51316_P050) |
Protein Size (# AA) |
553 amino acids |
Molecular Weight |
57kDa |
NCBI Gene Id |
4915 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Neurotrophic tyrosine kinase, receptor, type 2 |
Alias Symbols |
OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB |
Peptide Sequence |
Synthetic peptide located within the following region: DFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. |
Protein Interactions |
TNK2; RANBP9; POLR2G; HSP90AA1; AP1B1; NMNAT1; UBC; NTF4; Nedd4; SHC2; KIDINS220; DOK5; SH2B2; SH2B1; SHC3; RASGRF1; UBB; FRS3; GIPC1; NCK2; DYNLL1; SQSTM1; SHC1; NCK1; NTRK2; PTPN1; PTPN11; PLCG1; NTF3; NGFR; FYN; BDNF; TRAF6; PIK3R1; FRS2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NTRK2 (ARP51316_P050) antibody |
Blocking Peptide |
For anti-NTRK2 (ARP51316_P050) antibody is Catalog # AAP51316 (Previous Catalog # AAPP46572) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2 |
Uniprot ID |
Q8WXJ5 |
Protein Name |
BDNF/NT-3 growth factors receptor |
Protein Accession # |
NP_001018075 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001018065 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
NTRK2 |
Predicted Species Reactivity |
Human, Rat, Cow, Horse, Rabbit |
Application |
IF, WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 88%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Mouse brain
| Mouse brain |
| Image 2 | Human heart
| WB Suggested Anti-NTRK2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human heart |
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