| Product Number |
ARP50819_P050 |
| Product Page |
www.avivasysbio.com/gtf2a1l-antibody-c-terminal-region-arp50819-p050.html |
| Name |
GTF2A1L Antibody - C-terminal region (ARP50819_P050) |
| Protein Size (# AA) |
478 amino acids |
| Molecular Weight |
52kDa |
| NCBI Gene Id |
11036 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
General transcription factor IIA, 1-like |
| Alias Symbols |
ALF |
| Peptide Sequence |
Synthetic peptide located within the following region: RVTDDDIGEIIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kim,M., (2006) J. Biol. Chem. 281 (45), 34288-34298 |
| Description of Target |
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
| Protein Interactions |
GAB1; NKX2-3; ZBTB3; TLX3; MAFF; RBFOX2; HMG20A; PAX9; SIX6; MAFG; HOXC11; HOXC9; HOXA5; TLX2; EMX2; EMX1; CEBPE; ATF4; ASCL3; GTF2A2; SUB1; ID3; CSNK2A2; CSNK2A1; TBP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GTF2A1L (ARP50819_P050) antibody |
| Blocking Peptide |
For anti-GTF2A1L (ARP50819_P050) antibody is Catalog # AAP50819 (Previous Catalog # AAPS29911) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2A1L |
| Uniprot ID |
Q9UNN4 |
| Protein Name |
TFIIA-alpha and beta-like factor |
| Protein Accession # |
NP_006863 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006872 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GTF2A1L |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rat: 79% |
| Image 1 | Human HepG2
 | WB Suggested Anti-GTF2A1L Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
