| Product Number |
ARP50530_P050 |
| Product Page |
https://www.avivasysbio.com/yap1-antibody-c-terminal-region-arp50530-p050.html |
| Name |
YAP1 Antibody - C-terminal region (ARP50530_P050) |
| Protein Size (# AA) |
504 amino acids |
| Molecular Weight |
54kDa |
| NCBI Gene Id |
10413 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Yes-associated protein 1 |
| Description |
|
| Alias Symbols |
YAP, YKI, COB1, YAP2, YAP65 |
| Peptide Sequence |
Synthetic peptide located within the following region: QLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction. |
| Protein Interactions |
ABL1; TP73; RUNX1; AMOT; UBC; FBXW7; ARFIP1; RTF1; PAPOLA; PRMT3; TOM1; TSNAX; STAT1; MAP2K1; NF2; WBP2; RASSF8; YWHAQ; INADL; RAPGEF2; TJP2; SLC9A3R2; PDLIM7; LATS1; MPDZ; RAE1; ARID1A; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TP53BP2; TEAD3; TEAD1; SMARCD1; D |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-YAP1 (ARP50530_P050) antibody |
| Additional Information |
IHC Information: Human Prostate (formalin-fixed, paraffin-embedded) stained with YAP1 antibody ARP50530_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
IHC Information: Human Prostate (formalin-fixed, paraffin-embedded) stained with YAP1 antibody ARP50530_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. |
| Blocking Peptide |
For anti-YAP1 (ARP50530_P050) antibody is Catalog # AAP50530 (Previous Catalog # AAPP13823) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human YAP1 |
| Uniprot ID |
P46937 |
| Protein Name |
Yorkie homolog |
| Publications |
Guanglin Niu, Agnieszka B?k, Melanie Nusselt, Yue Zhang, Hubert Pausch, Tatiana Flisikowska, Angelika E Schnieke, Krzysztof Flisikowski. Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma.. Cancers (Basel). 13, (2021). IHC, ICC-IF, ICC 33803512
|
| Protein Accession # |
NP_001123617 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001130145 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
YAP1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Image 1 | Human Prostate
 | Immunohistochemistry with Human Prostate lysate tissue at an antibody concentration of 5.0ug/ml using anti-YAP1 antibody (ARP50530_P050) |
|
| Image 2 | Human Prostate
 | Human Prostate |
|
| Image 3 | Human Fetal Lung
 | Host: Rabbit
Target Name: YAP1
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
| Image 4 | HepG2, Human heart
 | Host: Rabbit
Target: YAP1
Positive control (+): HepG2 (HG)
Negative control (-): Human heart (HE)
Antibody concentration: 1ug/ml |
|
