SSX4B Antibody - middle region (ARP50423_P050)

Data Sheet
 
Product Number ARP50423_P050
Product Page www.avivasysbio.com/ssx4b-antibody-middle-region-arp50423-p050.html
Name SSX4B Antibody - middle region (ARP50423_P050)
Protein Size (# AA) 188 amino acids
Molecular Weight 22kDa
NCBI Gene Id 548313
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Synovial sarcoma, X breakpoint 4B
Alias Symbols CT5.4
Peptide Sequence Synthetic peptide located within the following region: MRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein Interactions HIF1A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SSX4B (ARP50423_P050) antibody
Blocking Peptide For anti-SSX4B (ARP50423_P050) antibody is Catalog # AAP50423 (Previous Catalog # AAPY02802)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SSX4B
Uniprot ID O60224
Protein Name Protein SSX4
Protein Accession # NP_001030004
Purification Affinity Purified
Nucleotide Accession # NM_001034832
Tested Species Reactivity Human
Gene Symbol SSX4B
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human kidney
WB Suggested Anti-SSX4B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human kidney
 

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