PAK2 Antibody - N-terminal region : FITC (ARP49217_P050-FITC)

Data Sheet
 
Product Number ARP49217_P050-FITC
Product Page www.avivasysbio.com/pak2-antibody-n-terminal-region-fitc-arp49217-p050-fitc.html
Name PAK2 Antibody - N-terminal region : FITC (ARP49217_P050-FITC)
Protein Size (# AA) 524 amino acids
Molecular Weight 57kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 5062
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols PAK65, PAKgamma
Peptide Sequence Synthetic peptide located within the following region: DNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Protein Interactions RHOJ; SORBS3; CDC42; UBC; NPEPPS; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TGM2; PFAS; PAFAH1B1; LDHB; ZFYVE19; UBFD1; UBE2R2; SCLY; ISOC1; ERP44; SFN; G6PD; EEF2; CKB; CAPNS1; PAK1; PAK2; HSPA5; RIOK3; MYC; APP; SH3RF3; ARHGEF7; SRC; LCK; HCK; RAC1; HIST1H4F;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-PAK2 (ARP49217_P050-FITC) antibody
Blocking Peptide For anti-PAK2 (ARP49217_P050-FITC) antibody is Catalog # AAP49217
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human PAK2
Uniprot ID Q13177
Protein Accession # NP_002568
Purification Affinity Purified
Gene Symbol PAK2
Predicted Species Reactivity Human
Application WB
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