| Product Number |
ARP48303_P050 |
| Product Page |
www.avivasysbio.com/ugp2-antibody-n-terminal-region-arp48303-p050.html |
| Name |
UGP2 Antibody - N-terminal region (ARP48303_P050) |
| Protein Size (# AA) |
497 amino acids |
| Molecular Weight |
56kDa |
| NCBI Gene Id |
7360 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
UDP-glucose pyrophosphorylase 2 |
| Alias Symbols |
UDPG, UGP1, DEE83, UDPGP, UGPP1, UGPP2, EIEE83, SVUGP2, UDPGP2, pHC379 |
| Peptide Sequence |
Synthetic peptide located within the following region: TKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) |
| Description of Target |
UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. |
| Protein Interactions |
GLRX3; ARIH2; UGP2; UBC; NUSAP1; PUF60; PACSIN2; FAF1; PAPOLA; HSPH1; NUDC; CARM1; FARSB; USP15; RANBP3; HIRIP3; CUL1; CSDE1; ZYX; TARS; TROVE2; SET; PTPN12; PPP2R5C; PPM1G; PLOD2; CC2D1B; VASN; PARVA; ILK; GART; BUB1B; LYN; CBS; MROH2B; DNPEP; ISG15; ABC |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-UGP2 (ARP48303_P050) antibody |
| Blocking Peptide |
For anti-UGP2 (ARP48303_P050) antibody is Catalog # AAP48303 (Previous Catalog # AAPY01673) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human UGP2 |
| Uniprot ID |
Q16851-2 |
| Protein Name |
UTP--glucose-1-phosphate uridylyltransferase |
| Sample Type Confirmation |
UGP2 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_001001521 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001001521 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
UGP2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-UGP2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateUGP2 is supported by BioGPS gene expression data to be expressed in HepG2 |
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