Product Number |
ARP48174_P050 |
Product Page |
www.avivasysbio.com/igfbp7-antibody-c-terminal-region-arp48174-p050.html |
Name |
IGFBP7 Antibody - C-terminal region (ARP48174_P050) |
Protein Size (# AA) |
282 amino acids |
Molecular Weight |
29 kDa |
NCBI Gene Id |
3490 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Insulin-like growth factor binding protein 7 |
Alias Symbols |
AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1 |
Peptide Sequence |
Synthetic peptide located within the following region: RGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Wajapeyee,N., (2008) Cell 132 (3), 363-374 |
Description of Target |
IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production. |
Protein Interactions |
RBBP8; HNF1A; RTN4; DSTN; UBC; CHMP3; CCL21; VEGFA; CCL5; SDC1; INS; IGF2; IGF1; CXCL10; INHBA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-IGFBP7 (ARP48174_P050) antibody |
Blocking Peptide |
For anti-IGFBP7 (ARP48174_P050) antibody is Catalog # AAP48174 (Previous Catalog # AAPY02582) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human IGFBP7 |
Uniprot ID |
Q16270 |
Protein Name |
Insulin-like growth factor-binding protein 7 |
Protein Accession # |
NP_001544 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001553 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
IGFBP7 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 93% |
Image 1 | Human Lung Tissue
| IGFBP7 antibody - C-terminal region (ARP48174_P050)
Catalog Number: ARP48174_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm and membrane of pneumocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
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Image 2 | Human Muscle
| WB Suggested Anti-IGFBP7 Antibody Titration: 0.2-1 ug/ml Positive Control: Human Muscle |
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Image 3 | Mouse Skeletal Muscle
| Host: Mouse Target Name: IGFBP7 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml |
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Image 4 |
| 25 ug of the indicated Mouse whole tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be slightly modified by both glycosylation and phosphorylation.
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