Product Number |
ARP48127_P050 |
Product Page |
www.avivasysbio.com/cd36-antibody-n-terminal-region-arp48127-p050.html |
Name |
CD36 Antibody - N-terminal region (ARP48127_P050) |
Protein Size (# AA) |
472 amino acids |
Molecular Weight |
53kDa |
NCBI Gene Id |
948 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
CD36 molecule (thrombospondin receptor) |
Alias Symbols |
FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3, BDPLT10 |
Peptide Sequence |
Synthetic peptide located within the following region: KTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bhr,C., (2008) Hum. Mol. Genet. 17 (11), 1695-1704 |
Description of Target |
CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency. The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Protein Interactions |
CHRD; APP; CAND1; ITGA2B; MATK; SRC; THBS1; ITGB3; LYN; YES1; ITGA6; CD9; FYN; ITGB1; COL1A2; COL1A1; VLDLR; LDLR; HSD11B1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CD36 (ARP48127_P050) antibody |
Blocking Peptide |
For anti-CD36 (ARP48127_P050) antibody is Catalog # AAP48127 (Previous Catalog # AAPP28011) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CD36 |
Uniprot ID |
P16671 |
Protein Name |
Platelet glycoprotein 4 |
Protein Accession # |
NP_001001547 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001001547 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
CD36 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 100% |
Image 1 | Human Liver
| WB Suggested Anti-CD36 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Liver |
|
Image 2 | Human Fetal Heart
| Host: Rabbit Target Name: CD36 Sample Type: Human Fetal Heart Antibody Dilution: 1.0ug/ml |
|
Image 3 | Human Fetal Liver
| Host: Rabbit Target Name: CD36 Sample Type: Human Fetal Liver Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0.12 |
|
Image 4 | Mouse Gut
| Mouse Gut |
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Image 5 | Human HepG2 Whole Cell
| Host: Rabbit Target Name: CD36 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml |
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