Product Number |
ARP48005_P050 |
Product Page |
www.avivasysbio.com/nr0b1-antibody-middle-region-arp48005-p050.html |
Name |
NR0B1 Antibody - middle region (ARP48005_P050) |
Protein Size (# AA) |
470 amino acids |
Molecular Weight |
52kDa |
NCBI Gene Id |
190 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Nuclear receptor subfamily 0, group B, member 1 |
Alias Symbols |
AHC, AHX, DSS, GTD, HHG, AHCH, DAX1, DAX-1, NROB1, SRXY2 |
Peptide Sequence |
Synthetic peptide located within the following region: FCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Mantovani,G., (2005) Fertil. Steril. 84 (5), 1542-1544 |
Description of Target |
NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. |
Protein Interactions |
NR5A1; ESRRG; RORA; RNF31; UBC; NR3C1; ESRRA; SNW1; PPARG; POU5F1; PGR; AR; COPS2; NRIP1; ESR2; SREBF1; ESR1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NR0B1 (ARP48005_P050) antibody |
Blocking Peptide |
For anti-NR0B1 (ARP48005_P050) antibody is Catalog # AAP48005 (Previous Catalog # AAPS20508) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NR0B1 |
Uniprot ID |
P51843 |
Protein Name |
Nuclear receptor subfamily 0 group B member 1 |
Protein Accession # |
NP_000466 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000475 |
Tested Species Reactivity |
Human |
Gene Symbol |
NR0B1 |
Predicted Species Reactivity |
Human |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-NR0B1 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate |
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