| Product Number |
ARP47590_P050 |
| Product Page |
www.avivasysbio.com/smc3-antibody-c-terminal-region-arp47590-p050.html |
| Name |
SMC3 Antibody - C-terminal region (ARP47590_P050) |
| Protein Size (# AA) |
681 amino acids |
| Molecular Weight |
74kDa |
| NCBI Gene Id |
9126 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Structural maintenance of chromosomes 3 |
| Alias Symbols |
BAM, BMH, HCAP, CDLS3, CSPG6, SMC3L1 |
| Peptide Sequence |
Synthetic peptide located within the following region: GKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. |
| Protein Interactions |
SUMO2; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; FBXO6; ANKRD28; HDAC11; HDAC8; HDAC9; SOX2; RAD21; CDCA5; PDS5A; WAPAL; MMS19; METTL21B; NOTCH1; SMC1A; SFPQ; HNRNPM; NSMCE2; UBD; COPS5; COPS6; CUL2; CUL3; NEDD8; CDK2; FBXO25; MECP2; NIPBL; CDK8; SUPT5H; P |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SMC3 (ARP47590_P050) antibody |
| Additional Information |
IHC Information: Paraffin embedded testis tissue, tested with an antibody dilution of 5 ug/ml. |
| Blocking Peptide |
For anti-SMC3 (ARP47590_P050) antibody is Catalog # AAP47590 (Previous Catalog # AAPP13005) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SMC3 |
| Uniprot ID |
Q9UQE7 |
| Protein Name |
Structural maintenance of chromosomes protein 3 |
| Sample Type Confirmation |
There is BioGPS gene expression data showing that SMC3 is expressed in HepG2 |
| Protein Accession # |
AAD32447 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005445 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SMC3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
| Image 1 | Human HepG2
 | WB Suggested Anti-SMC3 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that SMC3 is expressed in HepG2 |
|
| Image 2 | Human Testis
 | Testis |
|
