Product Number |
ARP46585_T100 |
Product Page |
www.avivasysbio.com/ddost-antibody-n-terminal-region-arp46585-t100.html |
Name |
DDOST Antibody - N-terminal region (ARP46585_T100) |
Protein Size (# AA) |
456 amino acids |
Molecular Weight |
46kDa |
NCBI Gene Id |
1650 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase |
Alias Symbols |
OST, WBP1, AGER1, CDG1R, GATD6, OST48, OKSWcl45 |
Peptide Sequence |
Synthetic peptide located within the following region: SPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Shibatani,T., (2005) Biochemistry 44 (16), 5982-5992 |
Description of Target |
DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. |
Protein Interactions |
HUWE1; VAPB; UBC; FAF1; STAU1; ASB11; TRIM13; SUZ12; EED; CLN3; NXT1; SRSF11; FN1; ATF2; STT3B; MAGT1; ZMPSTE24; VDAC2; SSR4; SSR3; SLC25A3; ILF2; KRTCAP2; FBXO6; UBD; AMFR; AUP1; TMEM173; UNC93B1; MAPK6; HDAC5; AGO3; BRCC3; GSTK1; TMBIM4; PGRMC1; SAP18; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-DDOST (ARP46585_T100) antibody |
Blocking Peptide |
For anti-DDOST (ARP46585_T100) antibody is Catalog # AAP46585 (Previous Catalog # AAPS19508) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST |
Uniprot ID |
Q5VWA5 |
Protein Name |
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit |
Protein Accession # |
NP_005207 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_005216 |
Tested Species Reactivity |
Human |
Gene Symbol |
DDOST |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
Image 1 | Human Jurkat
| WB Suggested Anti-DDOST Antibody Titration: 5.0ug/ml Positive Control: Jurkat cell lysate |
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