DDOST Antibody - N-terminal region (ARP46585_T100)

Data Sheet
 
Product Number ARP46585_T100
Product Page www.avivasysbio.com/ddost-antibody-n-terminal-region-arp46585-t100.html
Name DDOST Antibody - N-terminal region (ARP46585_T100)
Protein Size (# AA) 456 amino acids
Molecular Weight 46kDa
NCBI Gene Id 1650
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase
Alias Symbols OST, WBP1, AGER1, CDG1R, GATD6, OST48, OKSWcl45
Peptide Sequence Synthetic peptide located within the following region: SPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Shibatani,T., (2005) Biochemistry 44 (16), 5982-5992
Description of Target DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Protein Interactions HUWE1; VAPB; UBC; FAF1; STAU1; ASB11; TRIM13; SUZ12; EED; CLN3; NXT1; SRSF11; FN1; ATF2; STT3B; MAGT1; ZMPSTE24; VDAC2; SSR4; SSR3; SLC25A3; ILF2; KRTCAP2; FBXO6; UBD; AMFR; AUP1; TMEM173; UNC93B1; MAPK6; HDAC5; AGO3; BRCC3; GSTK1; TMBIM4; PGRMC1; SAP18;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-DDOST (ARP46585_T100) antibody
Blocking Peptide For anti-DDOST (ARP46585_T100) antibody is Catalog # AAP46585 (Previous Catalog # AAPS19508)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST
Uniprot ID Q5VWA5
Protein Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Protein Accession # NP_005207
Purification Protein A purified
Nucleotide Accession # NM_005216
Tested Species Reactivity Human
Gene Symbol DDOST
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Image 1
Human Jurkat
WB Suggested Anti-DDOST Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysate
 

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