| Product Number |
ARP46214_T100 |
| Product Page |
www.avivasysbio.com/swap70-antibody-n-terminal-region-arp46214-t100.html |
| Name |
SWAP70 Antibody - N-terminal region (ARP46214_T100) |
| Protein Size (# AA) |
585 amino acids |
| Molecular Weight |
69kDa |
| NCBI Gene Id |
23075 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
SWAP switching B-cell complex 70kDa subunit |
| Alias Symbols |
HSPC321, SWAP-70 |
| Peptide Sequence |
Synthetic peptide located within the following region: ALEEHFRDDDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Liu,J., (2007) J. Histochem. Cytochem. 55 (7), 701-708 |
| Description of Target |
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion. |
| Protein Interactions |
ZBTB5; RAPGEF4; UBC; CORO1B; ASUN; OTUD6B; JMJD6; GANAB; PACSIN2; FAF1; PAICS; FARSB; ZRANB2; RANBP3; CUL1; SUPT5H; SET; PPP2R5C; PLOD2; OSBP; GART; XRCC6; CRMP1; ATP6V1B2; C18orf8; CELSR3; IGHG1; PARP1; NPM1; NCL; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SWAP70 (ARP46214_T100) antibody |
| Blocking Peptide |
For anti-SWAP70 (ARP46214_T100) antibody is Catalog # AAP46214 (Previous Catalog # AAPP27049) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SWAP70 |
| Uniprot ID |
Q9UH65 |
| Protein Name |
Switch-associated protein 70 |
| Protein Accession # |
NP_055870 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_015055 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SWAP70 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-SWAP70 Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate |
|
