Product Number |
ARP46129_P050 |
Product Page |
www.avivasysbio.com/shmt2-antibody-c-terminal-region-arp46129-p050.html |
Name |
SHMT2 Antibody - C-terminal region (ARP46129_P050) |
Protein Size (# AA) |
504 amino acids |
Molecular Weight |
56kDa |
NCBI Gene Id |
6472 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Serine hydroxymethyltransferase 2 (mitochondrial) |
Alias Symbols |
GLYA, SHMT, NEDCASB, HEL-S-51e |
Peptide Sequence |
Synthetic peptide located within the following region: ELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Fu,T.F., (2001) Arch. Biochem. Biophys. 393 (1), 42-50 |
Description of Target |
SHMT2 plays a role in interconversion of serine and glycine. |
Protein Interactions |
CMTM5; ARL6IP1; HUWE1; UBC; MDM2; PSMG3; TBC1D15; SNX6; CAND1; VPS35; LUC7L2; CYHR1; ARFIP1; GSPT2; JMJD6; IVNS1ABP; ATG7; SEC24D; H1FX; CUL5; STAT1; SNX1; SHMT1; PAWR; NASP; IDE; HIST1H1B; CTTN; ATP6V1C1; APEH; ADRB2; ATF2; APP; CUL1; CUL3; NDRG1; HDAC5; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SHMT2 (ARP46129_P050) antibody |
Additional Information |
IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%. |
Blocking Peptide |
For anti-SHMT2 (ARP46129_P050) antibody is Catalog # AAP46129 (Previous Catalog # AAPP26991) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SHMT2 |
Uniprot ID |
P34897 |
Protein Name |
Serine hydroxymethyltransferase, mitochondrial |
Protein Accession # |
NP_005403 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005412 |
Tested Species Reactivity |
Human |
Gene Symbol |
SHMT2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human kidney
| Human kidney |
|
Image 2 | Human Liver Tissue
| SHMT2 antibody - C-terminal region (ARP46129_P050)
Catalog Number: ARP46129_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in Kupffer cells
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
Image 3 | Human HepG2
| WB Suggested Anti-SHMT2 Antibody Titration: 0.5ug/ml Positive Control: HepG2 cell lysate |
|