SHMT2 Antibody - C-terminal region (ARP46129_P050)

Data Sheet
 
Product Number ARP46129_P050
Product Page www.avivasysbio.com/shmt2-antibody-c-terminal-region-arp46129-p050.html
Name SHMT2 Antibody - C-terminal region (ARP46129_P050)
Protein Size (# AA) 504 amino acids
Molecular Weight 56kDa
NCBI Gene Id 6472
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Serine hydroxymethyltransferase 2 (mitochondrial)
Alias Symbols GLYA, SHMT, NEDCASB, HEL-S-51e
Peptide Sequence Synthetic peptide located within the following region: ELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Fu,T.F., (2001) Arch. Biochem. Biophys. 393 (1), 42-50
Description of Target SHMT2 plays a role in interconversion of serine and glycine.
Protein Interactions CMTM5; ARL6IP1; HUWE1; UBC; MDM2; PSMG3; TBC1D15; SNX6; CAND1; VPS35; LUC7L2; CYHR1; ARFIP1; GSPT2; JMJD6; IVNS1ABP; ATG7; SEC24D; H1FX; CUL5; STAT1; SNX1; SHMT1; PAWR; NASP; IDE; HIST1H1B; CTTN; ATP6V1C1; APEH; ADRB2; ATF2; APP; CUL1; CUL3; NDRG1; HDAC5;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SHMT2 (ARP46129_P050) antibody
Additional Information IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.
Blocking Peptide For anti-SHMT2 (ARP46129_P050) antibody is Catalog # AAP46129 (Previous Catalog # AAPP26991)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SHMT2
Uniprot ID P34897
Protein Name Serine hydroxymethyltransferase, mitochondrial
Protein Accession # NP_005403
Purification Affinity Purified
Nucleotide Accession # NM_005412
Tested Species Reactivity Human
Gene Symbol SHMT2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human kidney
Human kidney
Image 2
Human Liver Tissue
SHMT2 antibody - C-terminal region (ARP46129_P050)
Catalog Number: ARP46129_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in Kupffer cells
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Image 3
Human HepG2
WB Suggested Anti-SHMT2 Antibody Titration: 0.5ug/ml
Positive Control: HepG2 cell lysate
 

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