| Product Number |
ARP46037_P050 |
| Product Page |
www.avivasysbio.com/kynu-antibody-c-terminal-region-arp46037-p050.html |
| Name |
KYNU Antibody - C-terminal region (ARP46037_P050) |
| Protein Size (# AA) |
465 amino acids |
| Molecular Weight |
52kDa |
| NCBI Gene Id |
8942 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Kynureninase |
| Alias Symbols |
KYNUU, VCRL2 |
| Peptide Sequence |
Synthetic peptide located within the following region: LAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Suzuki,Y., Gene 200 (1-2), 149-156 (1997) |
| Description of Target |
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. |
| Protein Interactions |
LDHAL6B; BCCIP; CNDP2; NAGK; CHORDC1; C11orf58; NDRG1; GDA; SMS; RPS6KA1; PEPD; MVD; LDHA; GSR; GNS; CSE1L; ADSS; LYN; UBC; PALM2; SMEK2; SSU72; SIRT1; NUP210; SEC23IP; COIL; TPM3; SMARCD2; SGTA; PPM1G; ASNS; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KYNU (ARP46037_P050) antibody |
| Blocking Peptide |
For anti-KYNU (ARP46037_P050) antibody is Catalog # AAP46037 (Previous Catalog # AAPS16912) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KYNU |
| Uniprot ID |
Q16719 |
| Protein Name |
Kynureninase |
| Sample Type Confirmation |
KYNU is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_003928 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003937 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KYNU |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%; Yeast: 93% |
| Image 1 | Human Liver
 | Human Liver |
| | Image 2 | Human HepG2
 | WB Suggested Anti-KYNU Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysateKYNU is supported by BioGPS gene expression data to be expressed in HepG2 |
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